Publications & Reports

THE FOLLOWING ARE ARTICLES THAT HAVE BEEN PUBLISHED ON OUR WORK

AT BRAIN AND BODY FOUNDATION BY DR. DAVID AJIBADE AND COLLABORATORS

Defenseless & Exposed: Sickle Cell and the Immune System

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Abstract

Introduction:

According to statistics, about 70% of children with Sickle Cell Disorder (SCD) die before the age of five. In Nigeria, that’s about 100,000 deaths. This is tragic, but it is also preventable. Did you know that the commonest cause of death in SCD is infection?
These infections are also the commonest triggers for a crisis.

In countries like the USA and UK, provision is made for Sickle Cell Disorder (SCD) patients by including antibiotics and prophylaxis (like vaccines) against the frequently occurring infections in this demography.

In Nigeria, there is no such practice, and when you consider the fact that SCD warriors typically have weaker immune systems than their peers, then you can appreciate what a tragedy this truly is.

Having worked with hundreds of SCD warriors at the Foundation, we have been able to demonstrate that strengthening their immune systems can, in turn, significantly improve their quality of life and reduce their crises frequency and severity. We witness this every week at our free Friday clinics.

Thankfully, there are simple steps we can start taking to address this gap. We recommend safe immune system supplements such as vitamin C, vitamin D3, and zinc. These are all safe, readily affordable, require no prescription, and are widely available.

Most importantly, study after study has shown that most SCD warriors are severely deficient in these three nutrients.

Do you know anyone battling SCD? Send us a WhatsApp message +234 0806 365 6715 (CHATS ONLY, NO CALLS) or visit: www.brainandbodyfoundation.org

Abstract

Introduction:

A nutraceutical is a pharmaceutical-grade nutrient or nutrient complex that may be used for medicinal purposes. Most nutraceuticals are derived from plants and have been shown to be generally safe when used as food supplements. There is growing interest in the use of these natural products in delaying, ameliorating, and treating acute and chronic diseases. Ong W.Y. and co-editors in 2016 edited a special collection of reports on the beneficial effects of nutraceuticals in the management of neurodegenerative diseases and aging. However, there is a paucity of reports of their use in sub- Saharan Africa.

Case reports:

Here we describe a case series of some of the children managed at our center using nutraceuticals and other supportive care. Details of the observed effects are described in this report.

Discussion:

Globally, there is rising evidence of improved treatment outcomes with the use of nutraceuticals. Our experience in the management of Nigerian children with neurodevelopmental disorders suggests that they may be beneficial and are deserving of well-controlled studies. We hope that this case series will raise the interest of researchers in Nigeria in designing observational studies and clinical trials aimed at generating evidence for or against their use.

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