What Is Sickle Cell Disease?

Acemannan & Sickle Cell Disease

Acemannan provides the highest level of nature’s immune-activating molecules to help reboot your body’s immune functions.

Acemannan Research Findings:

1. Enhances immune system response to viruses and infections.

2. Increases stem cell production 300–400%.

3. Has a 10 fold impact on immune activation.


We propose to examine the role of the aloe vera leaf extract Acemannan to improve the quality of life and reduce complications of sickle cell disease patients. In addition, we also aim to establish it as an adjunct in the management of sickle cell disease.

The choice of natural products for the management of different conditions is increasing worldwide due to the effectiveness, affordability, and fewer side effects of such treatments.

Aloe vera is one of the most popular medicinal plants, widely used for the prevention or treatment of some cancers and skin, metabolic, and cardiovascular diseases throughout the world.

Ongoing Project: To demonstrate that strengthening the immune system can improve the quality of life of Children with SCD

The Problem:

Almost 200,000 children with sickle cell disease (SCD) are born each year.

50-75% of them will not live to see their fifth Birthday.

That’s over 100,000 deaths each year. Dead without ever having really lived. And this does not even tell the story of the survivors – those who have to live with the terrible effects of this terrible disease, day in, and day out.

The strokes, the pain, the fatigue, the blood transfusions, the recurrent and eventually permanent bone, and joint damage, etc.

And then, there are the crises in younger children (1- 6 years of age), a crisis usually occurs in one of two ways:

  • Sudden, excruciating bone pains – especially in the small bones of the hands and feet – otherwise called bone pain crises.

  • Sudden loss of blood volume, either by spontaneous large-scale disintegration/break up of red blood cells, or by sudden sequestration (or pooling) of blood into organs like the liver and spleen.

The former requires the infusion of fluids, pain relief, sedation, and treatment of infections. The latter requires, in addition, BLOOD TRANSFUSION. Both cases usually require hospital admission, sometimes for days.

And on and on it goes until they eventually die, usually before their 30th birthday.

Socioeconomic Burden:

The current numbers do not take into account the financial burden this illness places on caregivers, the healthcare system, and the economy as a whole…and it certainly doesn’t paint a picture of the psychological and emotional toll this takes on the sufferers and their loved ones.

We can end that suffering, and those needless deaths…easily. With your help.

Our Discovery:

Through our work at the foundation, we have been able to demonstrate that children and adults with Sickle Cell Disease (SCD) can see significant improvements in their quality of life if their immune systems are adequately supported and strengthened. To our knowledge, improvements like these have never before been seen in Nigeria, which has the highest number of cases of SCD in the world (click here to view sample video testimonials from our patients).